pentobarbital will decrease the extent or outcome of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Sodium valproate and valproic acid seem to lower barbiturate metabolism; therefore, barbiturate blood ranges needs to be monitored and ideal dosage changes built as indicated.
pentobarbital will lessen the extent or effect of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will reduce the extent or outcome of ritonavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lessen the level or outcome of terbinafine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the extent or result of cortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the extent or result of isradipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
pentobarbital will decrease the level or influence of oliceridine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. If coadministration that has a CYP3A4 inducer is essential, consider growing oliceridine dose right up until secure drug effects are accomplished; keep track of for signs of opioid withdrawal.
pentobarbital will decrease the extent or result of methadone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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pentobarbital will minimize the level or influence of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with solid CYP3A4 inducers isn't encouraged
pentobarbital will reduce the level or influence of itraconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Mysterious.
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pentobarbital will lessen the extent or effect of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.